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Understanding Type 2 Diabetes and Brain Health Study Guide

This guide explains the principles of functional Magnetic Resonance Imaging (fMRI) and its use in analyzing brain connectivity. It covers the Blood Oxygen Level Dependent (BOLD) signal, how functional and structural connections are identified using techniques like Diffusion Tensor Imaging (DTI) and tractography, and the application of network topology and graph theory to understand brain network parameters. The guide also discusses the clinical relevance of these methods, particularly in studyin

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Clinical Applications of (f)MRI in Brain Functioning

Clinical Applications of (f)MRI in Brain Functioning

Clinical applications of (f)MRI explore neurological disorders like epilepsy and conditions such as diabetes through neuroimaging of structure, function, and pathology.

  • Neurodegenerative disorders
  • Grey-matter atrophy
  • Functional MRI Techniques
  • Diffusion Tensor Imaging (DTI)
  • Arterial Spin Labeling (ASL)
  • Blood Brain Barrier permeability

fMRI Applications in Epilepsy and Connectivity

fMRI Applications in Epilepsy and Connectivity

Neurological disorder epilepsy, characterized by recurrent seizures and abnormal electrical activity in the brain, is examined through fMRI tasks, resting state fMRI, and treatment effects.

  • Epilepsy
  • Seizures
  • fMRI task
  • Resting state fMRI
  • BOLD noise
  • Independent component analysis
  • Network integrity
  • Motor network
  • Language network

fMRI Connectivity and Epilepsy Network Topology

Analysis of fMRI BOLD times-series and whole brain tractography connectome in chronic epilepsy using network topology and connectivity parameters.

  • fMRI
  • Epilepsy
  • Connectivity analysis
  • Whole brain connectivity
  • Cortex parcellation
  • BOLD times-series
  • Functional connection
  • Connectivity matrix
  • DTI
  • Tractography
  • Network Topology
  • Network parameters
  • Cryptogenic epilepsy
  • Mean path length

Type 2 Diabetes and Brain Integrity

Effects of Type 2 Diabetes on Brain

Type 2 Diabetes is a chronic metabolic condition characterized by insulin resistance and high blood sugar levels that may cause accelerated cognitive decline and white matter lesions.

  • Type 2 Diabetes Mellitus
  • Insulin resistance
  • Cognitive decline
  • White matter lesions
  • White matter volume loss
  • White matter tracts integrity
  • Prediabetes
  • Glucose metabolism status
  • Cerebrovascular and neurodegenerative changes

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