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If a fragment of a chromosome breaks off and then reattaches to the original chromosome at the same place but in the reverse direction, the resulting chromosomal abnormality is called _____. a) an inversion b) a reciprocal translocation c) a deletion d) a nondisjunction

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Although in humans there are 22 pairs of autosomal chromosomes, only three different chromosomal trisomies are commonly seen in newborns. Of the remaining 19 autosomes, many trisomies have not been seen in newborns. Why not?Although in humans there are 22 pairs of autosomal chromosomes, only three different chromosomal trisomies are commonly seen in newborns. Of the remaining 19 autosomes, many trisomies have not been seen in newborns. Why not? a) Trisomy for the other autosomal chromosomes is often lethal, and the affected embryos are miscarried. b) These autosomal chromosomes do not contain the same type of DNA or protein that makes up chromosomes susceptible to trisomy. c) Trisomy for these other autosomal chromosomes occurs so rarely that it has never been documented. d) Trisomy for these autosomal chromosomes has no effect and therefore would never be noticed.

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Use the graph and your knowledge of Down syndrome to select the three true statements. a) The number of infants born with Down syndrome increases at a steady rate from maternal age 25 to 50. b) The incidence of Down syndrome in infants born to mothers under the age of 35 is less than 0.5%. c) Down syndrome is caused by a trisomy of chromosome 21. d) The risk of having a baby with Down syndrome more than doubles for 45-year old mothers compared to 40-year old mothers. e) The largest five-year increase in the incidence of Down syndrome occurs between the maternal ages of 35 and 40.

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