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Cystic fibrosis (CF) is a disease based on mutations in the CF transmembrane conductance regulator (CFTR) gene. The codon sequence for part of the CFTR mRNA is:5' -ACC-ATT-AAA-GAA-TTT-AAT-ATC-ATT-GGT-GTT-TCC- 3'...where ACC codes for the amino acid threonine, which is the first amino acid encoded by the region of the gene shown. In some individuals with cystic fibrosis, the equivalent codon sequence is:5' -ACC-ATT-AAA-GAA-AAT-ATC-ATT-GGT-GTT-TCC- 3'Which of the following statements about this mutation is true?A. This is a missense mutation.B. This is an insertion mutation.C. This is an synonymous (silent) mutation.D. This is a frameshift mutation.E. This is a deletion mutation.
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