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Which of the following are correct statements about how enzymes work?- Enzymes catalyze specific chemical reactions because the shape of their active site allows only certain substrate molecules to enter. - The substrate(s) enter the enzyme active site in specific orientations. - The enzyme and the substrate(s) change shape, promoting a specific chemical reaction and then allowing the products to leave. - The first three answers are all correct. - Only the first two answers are correct.

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