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A subclass of an enzyme that converts an active PDC into an inactive one:
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- Enzyme activity is affected by pH because __________.-changes in pH can cause loss of cofactors from the enzyme-low pH will denature all enzymes-high or low pH may disrupt hydrogen bonding or ionic interactions and thus change the shape of the active site-the binding of hydrogen ions to the enzyme absorbs energy and thus there may not be enough energy to overcome the activation energy barrier-most substrates do not function well at high or low pH
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