Biochemistry Questions
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A positive standard reduction potential implies the products are favored over the reactants under standard conditions.TrueFalse
What is the terminal electron acceptor in aerobic organisms?UbiquinoneNAD+FADO2
Which reactions in the TCA cycle use a thioester substrate (a substrate with acetyl-CoA attached)?Steps 2 and 3Steps 1 and 5Steps 1 and 3
What does the reduction potential of 0.815 V for the reduction of oxygen to water indicate?water is a very strong reducing agentoxygen is a very strong oxidizing agentwater is a very strong reducing agent and oxygen is a very strong oxidizing agentwater will be spontaneously reduced to oxygen
Which of the following is activated by ADP?aconitasemalate dehydrogenasesuccinyl-CoA synthetaseisocitrate dehydrogenase
The reaction catalyzed by fumarase is _____.a dehydration of an alcohola hydration of an alkenea hydroxylation of an alkenean isomerization of an alcohol
Which of the enzymes of the TCA cycle contain an FAD cofactor?succinate dehydrogenaseisocitrate dehydrogenasea-ketoglutarate dehydrogenasemalate dehydrogenase
What cellular location contains pyruvate dehydrogenase and most of the citric acid cycle enzymes?mitochondrial matrixcytosolmitochondrial inter-membrane spaceinner mitochondrial membrane
The regulated enzymes of the TCA cycle include:Malate dehydrogenaseFumarase⍺-ketoglutarate dehydrogenaseCitrate lyase
Which of the following answers complete the sentence correctly?Succinate dehydrogenase...is a copper-sulfur protein.carries out an oxidative decarboxylation like isocitrate dehydrogenase.contains FAD and NAD+ cofactors like pyruvate dehydrogenase.is an integral membrane protein, unlike the other enzymes of the citric acid cycle.
Which of the enzymes listed below require NAD+?Glyceraldehyde-3-phosphate dehydrogenaseMalate dehydrogenaseIsocitrate dehydrogenaseSuccinate dehydrogenase
Which of the following condenses with oxaloacetate to form citrate?acetyl-CoAsuccinyl-phosphatecarboxybiotincis-aconitate
The first reaction of gluconeogenesis is:a carboxylationa redox reactiona phosphate transferan oxidative decarboxylation
Which of the following pyruvate dehydrogenase enzymes is correctly paired with the coenzyme that is associated with it?E3: FADE3: lipoamideE1: coenzyme AE2: thiamine pyrophosphate
What makes the reaction catalyzed by citrate synthase highly exergonic?hydrolysis of ATPconversion from keto to enol tautomerdecarboxylation reactionhydrolysis of thioester
Which of the following enzymes catalyzes the transfer of a phosphoryl group from ATP to glucose?aldolasephosphoglucose mutasehexokinaseglucose-6-phophatase
A major allosteric regulator of both glycolysis and gluconeogenesis is:2,3-bisphosphoglycerate1,3-bisphosphoglycerateFructose-1,6-bisphosphateFructose-2,6-bisphosphate
The steps in glycolysis that differ from those of gluconeogenesis are catalyzed by:Triose phosphate isomerase, phosphofructokinase, aldolasePyruvate kinase, phosphofructokinase, hexokinaseHexokinase, phosphofructokinase, aldolasePyruvate kinase, aldolase, enolase
What are the potential control points in glycolysis? What is the actual control point (commitment step)?Possible: 1, 4, 9: Actual: 1Possible: 1, 3, 10; Actual: 1Possible: 1, 3, 10; Actual: 3Possible: 2, 3, 9; Actual: 2
Glucose is converted to _____ in skeletal muscle under anaerobic conditions.LactateGlycogenAcetyl-CoAEthanol and CO2