Pharmacology of Gastrointestinal Drugs Study Guide
This guide covers the pharmacology of various drugs used to treat gastrointestinal conditions. It details the mechanisms of action, indications, side effects, adverse effects, and drug interactions for antiemetic drugs, drugs for peptic ulcer disease and GERD, laxatives, and medications for diarrhea and Irritable Bowel Syndrome (IBS).
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Pharmacology of Renal, Urinary, and Gastrointestinal Systems
Drugs Affecting Renal and Urinary Systems
List the names, actions, possible side effects, and adverse effects of diuretic drugs and medications used in the treatment of select renal disorders.
- Diuretic drugs
- Loop diuretics
- Potassium-sparing diuretics
- Aldosterone antagonists
- Urine output
- Blood pressure reduction
- Edema decrease
- Electrolyte imbalance
- Hypokalemia
- Hyperkalemia
- Ototoxicity
Pharmacological Treatments for Renal and Urinary Disorders
Drugs used in treating urinary problems, pyelonephritis, UTIs, glomerulonephritis, acute kidney injury, and chronic kidney disease.
- Benign prostatic hyperplasia
- Alpha-adrenergic receptor blockers
- Testosterone inhibitors
- Bladder anesthetics
- Urinary antispasmodics
- Overactive Bladder (OAB)
- Erectile Dysfunction
- Phosphodiesterase type 5 (PDE5) inhibitor
- Pyelonephritis
- Urinary Tract Infections (UTIs)
- Glomerulonephritis
- Acute Kidney Injury (AKI)
- Chronic Kidney Disease (CKD)
- Nephrotoxic medications
- End Stage Renal Disease (ESRD)
Pharmacological Treatments for Renal and Urinary Disorders
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Drugs for Gastrointestinal Problems
This content covers the names, actions, side effects, and adverse effects of drugs used for gastrointestinal problems, including antiemetics, promotility drugs, antacids, histamine H2 receptor blockers, proton-pump inhibitors, and cytoprotective drugs.
- Antiemetic drugs
- Serotonin (5-HT3) receptor antagonists
- Substance P/Neurokinin 1 receptor antagonists
- Phenothiazines
- Cannabinoids
- Promotility drugs
- Peptic ulcer disease drugs
- Gastroesophageal reflux disease (GERD) drugs
- Antacids
- Histamine H2-receptor antagonists
- Proton-pump inhibitors
- Cytoprotective drugs
- Digestive system functions
Pharmacology of Gastrointestinal Drugs
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Cytoprotective Drugs and Laxatives Pharmacology
This material covers cytoprotective drugs that protect the stomach lining and various drugs for constipation including bulk-forming, lubricant, stimulant, and hyperosmolar laxatives.
- Cytoprotective drugs
- Sucralfate
- Misoprostol
- Drugs for constipation
- Bulk-forming agents
- Lubricant laxatives
- Stimulant or irritant laxatives
- Stool softener
- Docusate
- Bisacodyl
- Mineral oil
- Psyllium
- Hyperosmolar laxatives
- Magnesium citrate
- Drug interactions
- Side effects and adverse reactions
Pharmacological Management of Diarrhea and IBS
Drugs for diarrhea and irritable bowel syndrome include anticholinergics, antispasmodics, opioid agonists, chloride channel activators, guanylate cyclase-C agonists, and serotonin 5HT-4 receptor agonists.
- Gastric motility
- Anticholinergics
- Antispasmodic antidiarrheals
- Diphenoxylate/atropine
- Dicyclomine
- Opioid agonists
- Irritable bowel syndrome (IBS-C and IBS-D)
- Chloride channel activators
- Lubiprostone
- Guanylate cyclase-C agonists
- Linaclotide
- Serotonin 5HT-4 receptor agonists
- Tegaserod
- Eluxadoline
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