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Guide to NSAIDs and Corticosteroids Study Guide

This guide explains the mechanisms of action for key lupus medications, including Cyclophosphamide, Azathioprine, and Belimumab. It covers how these drugs work at a cellular level to manage SLE, offering insights into targeted therapies and broad immunosuppression.

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Pharmacology for RA, Lupus, MS, and HIV

Pharmacology for RA and Lupus

Medications including corticosteroids, DMARDs, and NSAIDs are used to manage RA and lupus through mechanisms that suppress the immune system and decrease inflammation.

  • Prednisone
  • Hydroxychloroquine
  • Methotrexate
  • NSAIDs
  • Cyclophosphamide
  • Azathioprine
  • Belimumab
  • Mechanism of action
  • Nursing assessment
  • Monitoring
  • Patient education
  • Immune suppression
  • Inflammation reduction

Pharmacology of MS, Lupus, and HIV

This document details mechanisms of action, indications, nursing assessments, monitoring, and patient education for medications treating MS, lupus, RA, and HIV.

  • Mechanism of action
  • Nursing assessment
  • Monitoring
  • Patient education
  • Biologic DMARD
  • Immunosuppressant
  • Monoclonal Antibody
  • Muscle Relaxant
  • NRTIs
  • INSTIs
  • Protease Inhibitors
  • Entry/Fusion Inhibitors
  • Multiple Sclerosis medications
  • HIV antiretroviral therapy

NSAIDs and Corticosteroids

Detailed study of Prednisone and NSAIDs (Ibuprofen, Celecoxib, etc.) including mechanism of action, nursing assessments for GI/kidney function, and patient education regarding sudden cessation and bleeding risks.

DMARDs and Biologics

Comprehensive coverage of conventional DMARDs (Methotrexate, Hydroxychloroquine) and Biologics (Adalimumab, Belimumab) used in RA and Lupus, focusing on retinal toxicity, liver function, and infection monitoring.

Lupus Specific Therapies

In-depth look at Cyclophosphamide, Azathioprine, and Belimumab specifically for Lupus management, including DNA damage mechanisms and B-cell activity reduction.

MS Immunomodulators

Study of Mitoxantrone, Fingolimod, Cladribine, and Natalizumab, focusing on their unique mechanisms like S1P modulation and blocking immune cell crossing into the CNS.

MS Symptom Management

Pharmacology of muscle relaxants (Baclofen and Tizanidine) to manage spasticity and nerve signals in MS patients.

HIV Antiretroviral Therapy

Mastery of the different classes of HIV medications: NRTIs, NNRTIs, INSTIs, Protease Inhibitors, and Entry/Fusion Inhibitors.

HIV Nursing Care

Specific nursing assessments for HIV patients, including monitoring for anemia, liver function, CNS effects, and drug-supplement interactions.

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