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Cell Biology Fundamentals Study Guide

This guide covers the essential concepts of cell biology, including cell theory, prokaryotic and eukaryotic cell structures, the composition and function of cell membranes, and the mechanisms of transport across membranes. It also touches upon intracellular organization and the maintenance of a stable internal environment (homeostasis).

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Photosynthesis, Cellular Respiration, and Energy Conversion

Photosynthesis and Carbohydrate Production

Using sunlight to build carbohydrates through the two main stages of photosynthesis and the Calvin cycle.

  • Photosystems I and II
  • Chloroplast structure
  • Thylakoids
  • Chlorophyll
  • Accessory pigments
  • Photosynthetic electron transport chain
  • Linear electron flow
  • ATP and NADPH formation
  • Carbon fixation
  • Light absorption

Photosynthesis and Energy Conversion

  • Photosynthesis
  • Autotrophs
  • Phototrophs
  • Photoautotrophs
  • Electromagnetic radiation
  • Wavelength
  • Photons
  • Light reactions
  • Chloroplast

Linear Electron Flow and Photophosphorylation

This content explains linear electron flow during the light dependent reactions of photosynthesis to produce ATP and NADPH through photophosphorylation.

  • Linear electron flow
  • Photosystem I
  • Photosystem II
  • NADP+
  • ATP synthesis
  • Photophosphorylation
  • Electron transport chain
  • Water-splitting enzymes
  • Proton accumulation
  • Thylakoid membrane
  • Chemiosmosis
  • Chloroplasts

The Calvin Cycle and Photosynthesis

The Calvin cycle uses ATP and NADPH from light reactions to perform carbon fixation, reduction, and regeneration of RuBP to produce sugars.

  • Carboxylation
  • Reduction
  • Regeneration of RuBP
  • Carbon fixation
  • RuBP
  • ATP
  • Triose phosphate
  • Starch granules
  • Chloroplast stroma

Cellular Respiration and Redox Reactions

An explanation of oxidation and reduction reactions, electron transfer, and the oxidation of glucose during cellular respiration.

  • oxidation
  • reduction
  • redox reactions
  • cellular respiration
  • electron carriers
  • substrate level phosphorylation
  • oxidative phosphorylation
  • chemiosmosis
  • glucose oxidation
  • metal efflux transporter
  • copper homeostasis

Stages and Mechanisms of Cellular Respiration

Cellular respiration involves the oxidation of glucose to produce ATP, carbon dioxide, and water through glycolysis, pyruvate oxidation, the citric acid cycle, and oxidative phosphorylation.

  • cellular respiration
  • glycolysis
  • pyruvate oxidation
  • citric acid cycle
  • oxidative phosphorylation
  • ATP synthesis
  • electron carriers
  • NAD+
  • FAD
  • FADH2
  • oxidation
  • reduction
  • substrate-level phosphorylation
  • mitochondria
  • cytoplasm

Stages of Cellular Respiration

This content covers glycolysis, pyruvate oxidation, and the citric acid cycle during cellular respiration.

  • Glycolysis
  • Pyruvate oxidation
  • Citric acid cycle
  • Substrate-level phosphorylation
  • FADH2
  • Mitochondrial matrix
  • Acetyl-CoA
  • Oxidation
  • ATP production

Electron Transport and Oxidative Phosphorylation

  • Electron transport chain
  • Oxidative phosphorylation
  • ATP synthase
  • Proton gradient
  • Chemiosmosis
  • Redox reactions
  • Terminal electron acceptor
  • Active transport
  • Mitochondrial matrix
  • Intermembrane space

Cellular Respiration and Fermentation Processes

Processes including glycolysis, lactic acid fermentation, and ethanol fermentation regenerate NAD+ to synthesize ATP in the absence of oxygen.

  • Cellular respiration
  • Electron transport chain
  • ATP synthesis
  • Exergonic and endergonic pathways
  • Fermentation
  • Lactic acid fermentation
  • Ethanol fermentation
  • Glycolysis
  • Pyruvate reduction
  • NAD+ regeneration
  • Glucose oxidation

Glucose Storage and Cellular Respiration

Glucose molecules enter glycolysis or are stored as glycogen and starch to produce ATP through cellular respiration.

  • Glycogen storage
  • Glycolysis
  • ATP production
  • Cellular respiration
  • Triacylglycerols
  • Fatty acids
  • Glycerol
  • Acetyl CoA
  • Citric Acid Cycle
  • Electron transport chain
  • Fermentation
  • Pyruvate

Chemical Foundations and Biological Macromolecules

Biological Energy and Metabolic Processes

This content explores how cells utilize potential and kinetic energy, ATP, and metabolic classifications like anabolism and catabolism to perform cellular work.

  • Anabolism
  • Catabolism
  • Potential energy
  • Kinetic energy
  • Metabolic classification
  • Entropy
  • Gibbs free energy
  • Chemical energy
  • Enzymes
  • Catalysts

Gibbs Free Energy and Chemical Reactions

Reversible chemical reactions involve endergonic and exergonic processes characterized by changes in Gibbs free energy.

  • Reversible chemical reactions
  • Gibbs Free Energy (G)
  • Endergonic reactions
  • Exergonic reactions
  • Spontaneous reactions
  • Nonspontaneous reactions
  • Entropy (S)
  • Enthalpy (H)

Thermodynamics of Anabolic and Catabolic Reactions

This content explores ΔG in anabolic and catabolic reactions, ATP hydrolysis, and energetic coupling examples involving exergonic and endergonic reactions.

  • Anabolic and catabolic reactions
  • Gibbs free energy (ΔG)
  • ATP hydrolysis
  • Entropy (ΔS)
  • Enthalpy (ΔH)
  • Energetic coupling
  • Exergonic reaction
  • Endergonic reaction
  • Glucose 6-phosphate formation
  • Phosphoenolpyruvate and pyruvate

Enzyme Catalysis and Activation Energy

  • Activation energy
  • Enzyme catalysis
  • Transition state
  • Active site
  • Substrate
  • Enzyme-substrate complex
  • Enzyme-product complex
  • Protein folding
  • Catabolic reaction
  • Anabolic reaction
  • Reaction rate

Enzyme Active Site and Catalysis

Amino acids in the active site of an enzyme contribute to catalysis and substrate binding interactions.

  • amino acids
  • catalysis
  • active site
  • primary sequence
  • protein
  • substrate binding
  • hydrophilic
  • hydrophobic
  • histidine

Factors Affecting Enzyme Activity and Regulation

Enzyme activity is affected by environmental factors like temperature and pH, inhibitors, activators, negative feedback, and regulation of reaction components such as enzyme or substrate concentrations.

  • Enzyme activity regulation
  • Inhibitors
  • Activators
  • Negative Feedback
  • Temperature
  • pH
  • Enzyme denaturation
  • Optimal environments
  • Gene expression
  • Enzyme concentration
  • Substrate concentration
  • Enzyme saturation

Atomic Structure and Chemical Bonding

Subatomic particles, electron distribution, and the formation of covalent, ionic, and hydrogen bonds determine the chemical properties of atoms and molecules.

  • Atomic number
  • Atomic mass
  • Protons
  • Electrons
  • Atomic nucleus
  • Electron shells
  • Covalent bonds
  • Ionic bonds
  • Nonpolar covalent bonds
  • Polar covalent bonds
  • Electronegativity
  • Hydrogen bonds
  • Water molecular structure

Emergent Properties and Chemistry of Water

Water exhibits emergent properties including cohesion, adhesion, moderation of temperature, expansion as a solid, and acting as a versatile solvent.

  • cohesion
  • adhesion
  • surface tension
  • moderation of temperature
  • high specific heat
  • evaporative cooling
  • density of ice
  • versatile solvent
  • hydrophilic
  • hydrophobic
  • pH scale
  • hydrogen ion concentration
  • acids
  • bases
  • self ionization of water

Molecules of Life and Protein Structure

Organic molecules containing carbon form the biological backbone of life through various functional groups and large macromolecules.

  • carbon-based life
  • covalent bonds
  • functional groups
  • macromolecules
  • monomers
  • polymers
  • dehydration synthesis
  • hydrolysis
  • amino acids
  • primary structure
  • secondary structure
  • tertiary structure
  • quaternary structure
  • hydrophobic amino acids
  • hydrophilic amino acids

Structure and Composition of Nucleic Acids

Nucleic acids are polymers called polynucleotides made of nucleotide monomers consisting of a nitrogenous base, a pentose sugar, and a phosphate group.

  • nucleotides
  • polynucleotides
  • nitrogenous bases
  • pyrimidines
  • purines
  • ribose
  • deoxyribose
  • nucleoside
  • phosphodiester linkage
  • sugar-phosphate backbone
  • complementary base pairing
  • hydrogen bonds
  • antiparallel

Molecules of Life: Carbohydrates

Carbohydrates serve as an immediate energy source and include monosaccharides, disaccharides, and polysaccharides such as starch, glycogen, cellulose, and chitin.

  • Carbohydrates
  • Monosaccharides
  • Disaccharides
  • Polysaccharides
  • Isomers
  • Glycosidic bonds
  • Starch
  • Glycogen
  • Cellulose
  • Glucose
  • Galactose
  • Fructose

Structure and Function of Lipids

Lipids are hydrophobic organic molecules including fatty acids, triacylglycerols, phospholipids, and steroids.

  • hydrophobic hydrocarbons
  • dehydration reactions
  • fatty acids
  • triacylglycerols
  • adipose cells
  • saturated versus unsaturated fatty acids
  • phospholipids
  • cholesterol
  • steroids
  • hormones

Scientific Inquiry, Hypothesis Testing, and Molecular Foundations

Understanding Scientific Inquiry and Method

This content explores the scientific method, scientific inquiry, and the process of formulating and testing hypotheses through investigation, exploration, and communication.

  • scientific method
  • scientific inquiry
  • formulating and testing hypotheses
  • controlled experiments
  • independent and dependent variables
  • repeatable observations
  • testable hypotheses
  • placebo
  • control group
  • exploration
  • investigation
  • communication
  • gathering and interpreting data
  • establishing a theory
  • natural world

Forming and Testing Scientific Hypotheses

This content explains how to form and test hypotheses, make predictions, and gather qualitative or quantitative data through controlled experiments.

  • hypothesis
  • experiment
  • prediction
  • independent variable
  • dependent variable
  • qualitative data
  • quantitative data
  • controlled experiment
  • experimental group
  • control group
  • controlled variables
  • testable
  • falsifiable

Ethics, Bias, and Scientific Theory

This content examines medical racism, systemic racial disparities in research funding, and the distinction between scientific theories and laws.

  • medical racism
  • Tuskegee syphilis study
  • unethical prisoner experiments
  • forced sterilization
  • systemic racial disparities in funding
  • peer review
  • scientific method
  • scientific theory
  • scientific law
  • theory of evolution by natural selection
  • cell theory
  • anthropogenic climate change theory
  • germ theory
  • gene theory

Scientific Inquiry and Hypothesis Testing

A case study investigates how coat coloration in mouse populations serves as an adaptation for camouflage against predators through scientific inquiry.

  • scientific inquiry
  • hypothesis
  • prediction
  • natural selection
  • adaptation
  • camouflage
  • predation
  • independent variable
  • experimental models

Scientific Method and Experimental Design

An analysis of experimental results involving caffeine consumption, treatment groups, control groups, and double-blind experiments.

  • double-blind experiment
  • treatment groups
  • control group
  • dependent variable
  • descriptive observational study
  • cause and effect

The Molecules of Life

An exploration of atoms, subatomic particles, ions, and chemical bonds.

  • atoms
  • subatomic particles
  • covalent bonds
  • ionic bonds
  • hydrogen bonds
  • elements
  • protons
  • electrons

Cell Structure, Membranes, and Transport Mechanisms

Cells, Membranes, and Homeostasis

This content compares prokaryotic and eukaryotic cells, identifies major intracellular structures, and describes biological membrane functions including osmosis and diffusion.

  • Prokaryotic cells
  • Eukaryotic cells
  • Cell theory
  • Cell membrane
  • Cytoplasm
  • Cytosol
  • Cytoskeleton
  • Ribosomes
  • Chromosomes
  • Organelles
  • Nucleus
  • Endomembrane system
  • Mitochondria
  • Chloroplasts
  • Osmosis
  • Diffusion
  • Simple diffusion
  • Facilitated diffusion
  • Active transport

Phospholipid Bilayers and Membrane Structure

Phospholipids are amphipathic molecules that spontaneously form lipid bilayers and liposomes to create cell membranes.

  • phospholipids
  • liposome
  • cholesterol
  • membrane fluidity
  • fluid mosaic model
  • saturated fatty acids
  • unsaturated fatty acids
  • integral membrane proteins
  • peripheral proteins
  • transmembrane proteins
  • glycolipids
  • glycoproteins

Cell Water Balance and Tonicity

Tonicity is the ability of a surrounding solution to cause a cell to gain or lose water through osmosis.

  • Tonicity
  • Isotonic solution
  • Hypertonic solution
  • Hypotonic solution
  • Osmosis
  • Lysis
  • Active transport
  • Contractile vacuole
  • Cell wall
  • Turgor pressure

Cell Membrane Permeability and Transport Mechanisms

  • Permeability of phospholipid bilayers
  • Facilitated diffusion
  • Channel proteins
  • Carrier proteins
  • Active transport
  • Primary active transport
  • Secondary active transport
  • Sodium-potassium pump
  • ATP hydrolysis
  • Concentration gradient
  • Uniporter
  • Symporter
  • Antiporter

Cell Organelles and the Endomembrane System

This content compares prokaryotic and eukaryotic cells and identifies major intracellular structures including the endomembrane system, mitochondria, and chloroplasts.

  • Prokaryotic cells
  • Eukaryotic cells
  • Endomembrane system
  • Nuclear envelope
  • Endoplasmic reticulum
  • Rough endoplasmic reticulum
  • Smooth endoplasmic reticulum
  • Golgi apparatus
  • Lysosomes
  • Vesicles
  • Exocytosis
  • Endocytosis
  • Mitochondria
  • Chloroplasts
  • Ribosomes
  • Cell membrane
  • Cell wall

Structure and Function of the Cytoskeleton

The cytoskeleton is formed from long chains of protein subunits that provide internal structural support and enable movement of substances within the cell.

  • cytoskeleton
  • microtubules
  • microfilaments
  • intermediate filaments
  • tubulin dimers
  • actin monomers
  • centrosome
  • flagella
  • cell division
  • muscle contraction
  • cytokinesis

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