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What is the basis for the difference in how the leading and lagging strands of DNA molecules are synthesized?A: DNA polymerase can join new nucleotides only to the 3′3′ end of a preexisting strand, and the strands are antiparallel.B: The origins of replication occur only at the 5′5′ end.C: DNA ligase works only in the 3′3′ →→ 5′5′ direction.D: Helicases and single-strand binding proteins work at the 5′5′ end.
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