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Sepsis by generating a severe inflammatory response via outer membrane lipooligosaccharide (LOS), which then increases capillary permeability which then causes hypovolemia, thus causing septic shockHemorrhagic skin lesions (e.g. petechiae, purpura)Waterhouse-Friderichsen syndrome is a serious complication that is characterized by bilateral adrenal hemorrhage → adrenal insufficiency
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