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galvas smadzeņu kavernozo sinusu trombozi ar sekojošu meningītu var izraisīt retrogrāda ādas infekcijas izplatība no sejas bīstamā trijstūra, jo:1. sejas vēnas šajā apvidū anastomozē ar v.ophthalmica superior un v.ophthalmica inferior, kuras tieši drenējas smadzeņu kavernozajos sinusos2. sejas artērijas šajā apvidū anastomozē ar a.supraorbitalis un a.infraorbitale, kuras tieši drenējas smadzeņu kavernozajos sinusos
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