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→ débute lorsque l'odontoblaste devient fonctionnel→ constitue la majeure partie de la masse dentinaire → forme la partie externe de l'orthodentine → produite pendant la formation de la dent 4µm/jour→ donne la forme générale de la couronne et la racine → à la fin de l'apexogenèse, les odontoblastes ralentissent la synthèse
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