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An interesting procedure has been applied for assessing the chromosomal balance of potential secondary oocytes for use in human in vitro fertilization. Using fluorescence in situ hybridization(FISH), Kuliev and Verlinsky (2004) were able to identify individual chromosomes in first polar bodies and thereby infer the chromosomal makeup of "sister" oocytes. Suppose that a mother had a normal chromosomal composition, but that when examining a first polar body you saw that it had one dyad of each chromosome but two dyads of chromosome 21. What would you expect to be the status of chromosomal 21 in the secondary oocyte?
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