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31. A 32 yo woman with the known Neurofibromatosis I (NFI) has cafe-au-lait patches scattered throughout her skin, but is otherwise without signs or symptoms of the disease. Her older brother, also with the NFl gene has multiple skin nodules and severe seizures. The disease if fully penetrant, so what explains the difference in the presentation of the two siblings.a. variable expressivity of the NFl geneb. x-linking of the diseasec. gene silencingd. multifactorial conditionse. somatic hyper mutation of the NFl gene

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