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Oncology Questions

Explore questions in the Oncology category that you can ask Spark.E!

Panitumumab is a fully human monoclonal antibody that is directed against which receptor?

Antimetabolites are structurally similar to endogenous compounds that are antagonists of which molecule?

Asparaginase depletes serum levels of which molecule?

Ziv-aflibercept works similarly to bevacizumab in that it targets which molecule?

Antimetabolites act in which phase of the cell cycle?

True/False: Direct acid neutralizers are used to neutralize 100% of acidity and have bactericidal activity of H. pylori.

Cetuximab is a chimeric monoclonal antibody that is directed to the extracellular domain of which receptor?

What type of drug is indicated by the suffix -ximab?

Are natural product anticancer drugs CCS or CCNS?

Bleomycin is composed of a mixture of which molecules?

TKIs inhibit TK activity of which specific gene?

Podophyllotoxins act during which phase of the cell cycle?

What type of drug is indicated by the suffix -tinib?

H. pylori or NSAID induced PUD?- Inhibition of COX --> Decreased PGE2 --> Increased acid secretion- Increased ICAM --> Mucosal damage via neutrophils- Trapped as an ion in epithelial cell --> Cellular injury

What type of drug is indicated by the suffix -zumab?

Ziv-aflibercept is used in treatment of which cancer?

What is the adverse effect of sodium bicarbonate and calcium carbonate?

Gefitinib and erlotinib are small molecule inhibitors of what?

Cytarabine is activated by kinases into which molecule that inhibits DNA polymerases?

Fluorouracil MOA:- Incorporation of _____ into DNA --> Inhibits _____ synthesis and function- Incorporation of _____ into RNA --> Inhibits _____ processing and function

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