Immunology Questions
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The virus in which Helper T cells get destroyed
The immunological consequence of severe combined immunodeficiency disease (SCID) caused by a genetic defect in either RAG-1 or RAG-2 genes islack of somatic recombination in T-cell receptor and immunoglobulin gene locilack of somatic recombination in T-cell receptor locilack of somatic recombination in immunoglobulin locilack of somatic hypermutation in T-cell receptor and immunoglobulin locilack of somatic hypermutation in T-cell receptor loci.
What are the three classes of MHC molecules?
From what we learned in class which of these statements is FALSE regarding Omenn syndrome?A genetic defect results in reduced activity in the RAG proteinsA viable therapy for this disease is to perform a bone marrow transplantInfants with Omenn syndrome initially appear normal and healthy but symptoms emerge soon afterwardsAntigen processing and presentation via MHC I and II is defectiveThe overall TCR diversity in Omenn syndrome patients is lower then the TCR diversity in the average population
The role of the CD3 proteins and ζ chain on the surface of the cell is totransduce signals to the interior of the T cellbind to antigen associated with MHC moleculesbind to MHC moleculesbind to CD4 or CD8 moleculesfacilitate antigen processing of antigens that bind to the surface of T cells.
What immune responses are rapid? Which require several days?
1. stimulates lymphocyte proliferation2. more co-stimulatory molecules are produced on the cell 3. can be effective for a longer amount of time 4. increases local inflammation
What happens when damaged or foreign antigens are present for MHC I protein?
T/F: Without TH, there is no immune sytem
What occurs during the faciliation of helper T cell lymphocytes (CD4+)?
Which hypersensitivity is T-cell mediated
What causes immediate and subacute hypersensitivities
What does the neuraminidase antigen do for the flu virus?
B cells cannot become activated and form clones of themselves without
Which hypersensitivity reactions are antibody mediated?
How many more bacterial cells are there in the human body than body cells?
how are endosomal proteases activated to degrade antigen into peptides?
peptides of cytosolic pathogens bind to which class MHC?
peptides of intravesicular pathogens bind to which class MHC?
peptides of extracellular pathogens and toxins bind to which class MHC?