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the placenta develops from which type of cells?
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- Possible mechanism of action as to how harm is caused include: • May be beneficial or harmless to the mothers but harmful or lethal to the embryo or the foetus• Time of exposure is critically important • Susceptibility may be genetically determined • It is usually dose dependent • Agents may be synergistic • A specific placental barrier does not exist • Risk may be altered by individual variation in drug pharmacokinetic metabolism
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